The Apex clinical trial is evaluating an investigational medication for the treatment of adults, 18 years of age and older, with Advanced Systemic Mastocytosis (AdvSM), a rare, aggressive, life-threatening disease caused by the abnormal accumulation of mast cells in different organs, primarily in skin and bone marrow. Patients diagnosed with AdvSM have evidence of organ involvement with organ dysfunction, such as evidence of bone marrow failure, an enlarged spleen, and/or enlarged liver with liver function test abnormalities.*
*Based on World Health Organization (WHO) “C-findings”